Podcast

Episode 84: The Link Between Addiction and Inflammation w. Dr. Gupreet Padda, MD (ep 84)

EA
Erik Abramowitz
78 min

Dr. Gupreet Padda, a distinguished addiction specialist and experienced biohacker, joins us to explore the intricate relationship between inflammation and addiction. Drawing from his extensive clinical experience, Dr. Padda shares evidence-based insights into how metabolism, inflammation, and mental health interconnect in ways that challenge traditional understanding of addiction and chronic disease.

Topics Discussed

Inflammation and Addiction Connection

  • The fundamental role of inflammation in chronic disease development

  • Critical analysis of conventional addiction research

  • Evolutionary perspective on inflammatory response

  • Patterns of neuroinflammation across different populations

Metabolic Health and Mental Wellness

  • Understanding the insulin resistance-addiction relationship

  • Neurotransmitter pathway responses to different sugars:

    • Fructose’s effects on dopamine systems

    • Glucose’s influence on serotonin pathways

  • The insulin resistance connection to Alzheimer’s disease

  • Exploring the gut-brain axis in mental health

Cholesterol and Lipid Metabolism

  • Understanding cholesterol’s beneficial roles

  • Differentiating between LDL-C and LDL-P measurements

  • Uric acid’s anti-inflammatory properties

  • Comparing effects of Omega-3 versus Omega-6 fatty acids

Clinical Applications and Treatment Approaches

  • Essential insulin markers: C-peptide and insulin testing

  • Understanding antidepressant mechanisms through gut function

  • Metformin’s therapeutic action via gut pathways

  • Historical context of insulin development and usage

About Dr. Padda

Dr. Gupreet Padda combines traditional medical approaches with evidence-based integrative methods in his specialization in addiction medicine and pain management. His research and clinical work focus on understanding the metabolic and inflammatory components of chronic conditions and mental health disorders.

Learn more about Dr. Padda’s work:

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Disclaimer: This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare provider before starting any supplement regimen.