Phenibut
GABAergics

Phenibut

The typical dosage range for Phenibut is between 250 mg to 1500 mg per day
Synthetic NootropicsRussian/Soviet Compounds
Erik Abramowitz, FNTP
Reviewed by Erik Abramowitz, FNTP Last updated February 4, 2026
Regulatory Warning: This substance is subject to active FDA enforcement action, has been involved in federal criminal prosecutions, or is classified as unsafe for sale as a dietary supplement. This page is retained for educational and harm-reduction purposes only. Do not purchase or consume this substance based on information found here.

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Overview

Phenibut is a synthetic derivative of the neurotransmitter GABA (gamma-aminobutyric acid). It is primarily used for its anxiolytic and nootropic effects, promoting relaxation, reducing anxiety, and enhancing cognitive function.

Dosage

The typical dosage range for Phenibut is between 250 mg to 1500 mg per day, often taken in divided doses. It is recommended to take it on an empty stomach for optimal absorption, and users should be cautious of tolerance and potential withdrawal effects with prolonged use.

Recommended Phenibut Products

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Phenibut FAA Capsules by Research Chemical Depot

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Research & Studies

This section includes 7 peer-reviewed studies referenced in our analysis.

[Dissociation of the anti-amnesic and antihypoxic effects of nootropic and antihypoxic preparations].

1987
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Phenibut dependence.

2013DOI: 10.1136/bcr-2012-008381
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Acute behavioural disturbance associated with phenibut purchased via an internet supplier.

2015DOI: 10.3109/15563650.2015.1059945
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Acute phenibut withdrawal: A comprehensive literature review and illustrative case report.

2019DOI: 10.17305/bjbms.2018.4008
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Phenibut (β-Phenyl-γ-Aminobutyric Acid): an Easily Obtainable "Dietary Supplement" With Propensities for Physical Dependence and Addiction.

2020DOI: 10.1007/s11920-019-1009-0
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Phenibut Addiction in a Patient with Substance Use Disorder.

2019DOI: 10.7759/cureus.5230
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Toxidrome of an Easily Obtainable Nootropic: A Case Report of Phenibut Intoxication and Withdrawal Delirium.

2023DOI: 10.1097/JCP.0000000000001759
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Medical Disclaimer: This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a qualified healthcare provider before starting any supplement regimen.
Reference ID: 306 Updated: Feb 4, 2026